Description
CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two
CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ)
heterodimer. It is found on all mature T cells, NKT cells, and some thymocytes. CD3, also
known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen
recognition, signal transduction, and T cell activation.